ProgenaMatrix is an active wound matrix manufactured from human keratin and numerous other proteins. Immediately upon application, ProgenaMatrix creates a barrier to maintain an environment important for the healing process – with no delay. The unique characteristics of ProgenaMatrix make it a biocompatible primary wound matrix and protective barrier; it is intended for use in dry, light, and moderately exuding partial and full-thickness wounds.
Until recently, keratin has long been considered to have the singular function of providing structure to cells and tissue. Now, Cell Constructs has identified another important function for human keratin – an active wound matrix. It’s estimated that 14 million people suffer from chronic wounds annually. Complications from chronic wounds can lead to debilitating and life-threatening complications as well as increased healthcare costs.1
1. Armstrong DG, Boulton AJM, Bus SA. Diabetic foot ulcers and their recurrence. N Engl J Med 2017;376:2367-7.
The unique characteristics of ProgenaMatrix make it a biocompatible primary wound matrix and protective barrier. ProgenaMatrix is engineered to be transparent, allowing for wound visualization during treatment. ProgenaMatrix is packaged fully hydrated and capable of maintaining moisture in the wound bed. As healing progresses and wound margins shrink, ProgenaMatrix is designed to lift up and away as tissue heals, which can reduce the risk of maceration by limiting contact with the peri-wound tissue.1
1. Mikel G, Weir D. Prevention and Treatment of Moisture-Associated Skin Damage (Maceration) in the Periwound Skin. Journal of Wound, Ostomy, and Continence Nursing. 2007; 34, 2: 153-157.
Cell Constructs uses pure human keratin selectively extracted from hair as a starting material to construct sterile implants and matrices. This technology is covered by a recently issued United States Patent (US 9,072,818). Other patents are pending.
ProgenaMatrix is currently undergoing a 510k premarket review by FDA for dry, light and moderately exuding partial and full thickness wounds. Not available for sale or other clinical use.